Title: Indigenous, Traditional Medicinal Therapies as Cancer Complication Remediation and Palliative Support for Cachexia.
What is Cachexia?
‘Cachexia; from Greek κακός kakos “bad” and ἕξις hexis “condition”) or wasting syndrome is loss of weight, muscle atrophy, fatigue, weakness, and significant loss of appetite in someone who is not actively trying to lose weight. Cachexia is also known or seen in patients with cancer, AIDS, chronic obstructive pulmonary disease, multiple sclerosis, congestive heart failure, tuberculosis, familial amyloid polyneuropathy, malaria, mercury poisoning (acrodynia) and hormonal deficiency. It is a positive risk factor for death, meaning if the patient has cachexia, the chance of death from the underlying condition is increased dramatically. About 50% of all cancer patients suffer from cachexia.
The exact mechanism in which these diseases cause cachexia is poorly understood and may vary from one individual to another, but there is probably a role for inflammatory cytokines, such as tumor necrosis factor-alpha (which is also nicknamed ‘cachexin’ or ‘cachectin’), interferon gamma and interleukin 6, as well as the tumor-secreted proteolysis-inducing factor. Side effects of chemotherapy drug regimen and or radiation therapy may be causes. Categories of physical/ biological adverse and or side effects of conventional Cancer therapies: include Edema, Inflammation, Neuropathies and Neuralgias, Immune suppression. Severe, possibly long term chronic malnutrition may be a factor.
1) Can Indigenous and traditional, native medicine practices and or evolving therapies derived from Indigenous culture traditions make a positive contribution towards Cancer complication remediation and palliative care?